People 65 years and older and those who are moderately or severely immunocompromised should receive a second dose of 2024-2025 COVID-19 vaccine six months after their first dose. See the CDC's updated guidance. More Info
No. They do not affect or interact with our DNA in any way. Your body naturally breaks down everything in the vaccine. There is no COVID-19 virus in the vaccine, and none of the vaccines can change your DNA.